ORC6 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A5426-20, A5426-100
Citations, Manuals and SDS Available upon request.
Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
Synonyms: ORC6L; ORC6
GeneID: 23594
Swiss-Prot: Q9Y5N6
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 28kDa
Observed Molecular Weight: 28kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human ORC6 (NP_055136.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Jurkat, SW620, PC-3, HeLa, Mouse brain, Rat brain
Cellular Location: Nucleus
Category: Polyclonal Antibodies
Citations, Manuals and SDS Available upon request.