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OSBL8 rabbit pAb - ES14365

OSBL8 rabbit pAb - ES14365

Regular price $207.20 CAD
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OSBL8 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14365-50, ES14365-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human OSBL8 AA range: 290-340

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 114882

Human SWISS Prot NO: Q9BZF1

Subcellular Location: [Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane. The presence of the N-terminus extension contains an overall negative charge that may explain the weak localization to the cortical endoplasmic reticulum (Probable).; [Isoform 3]: Endoplasmic reticulum membrane; Single-pass membrane protein. Localizes to the cortical endoplasmic reticulum at the endoplasmic reticulum-plasma membrane contact sites.

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