OSCAR Polyclonal Antibody - BT-AP12553

OSCAR Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12553-20, BT-AP12553-50, BT-AP12553-100

Citations, Manuals and MSDS Available upon request.

Background: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Immunology; Signal transduction; Tags and cell markers

Target Protein: OSCAR

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Osteoclast-associated immunoglobulin-like receptor

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8IYS5; Mouse: Q8VBT3

Synonyms: Osteoclast-associated immunoglobulin-like receptor;Osteoclast-associated receptor;hOSCAR;Polymeric immunoglobulin receptor 3;PIgR-3;PIgR3;Poly-Ig receptor 3

GeneID: Human: 126014

Research Use Only