Product Description

OSGEP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8931-50, BS8931-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NPF4

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: Osgep (O-sialoglycoprotein endopeptidase), also known as GCPL1, is a 335 amino acid protein that is a member of the peptidase M22 family. Osgep specifically cleaves the 31-Arg-l-Asp-32 bond in glycophorin A, but it does not cleave desialylated glycoproteins, unglycosylated proteins or glycoproteins that are only N-glycosylated. Though ubiquitously expressed at low levels, highest levels of Osgep are found in liver, skeletal muscle and kidney. OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as three alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: OSGEP polyclonal antibody detects endogenous levels of OSGEP protein.

Bioworld Molecular Weight: ~ 36kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cell lines, using OSGEP antibody.

Alternative Name: Probable tRNA N6-adenosine threonylcarbamoyltransferaseUniRule annotation; N6-L-threonylcarbamoyladenine synthase; t(6)A synthase; O-sialoglycoprotein endopeptidaseUniRule annotation; hOSGEP; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPUniRule annotation; OSGEP; GCPL1

Immunogen: Recombinant full length Human OSGEP.

Conjugate: Unconjugated

Modification: Unmodified