Product Description

OST48 Polyclonal Antibody

Catalogue Numbers: BS67346-50, BS67346-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P39656

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB (1/500 - 1/2000), IHC (1/50 - 1/200)

Background: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.
N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity).Required for the assembly of both SST3A- and SS3B-containing OST complexes.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of OST48 protein.

Extra Notes: Western blot analysis of OST48 expression in HepG2 (A), A549 (B), mouse brain (C), rat testis (D) whole cell lysates.

Bioworld Molecular Weight: ~51 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: KIAA0115; OST48; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; DDOST 48 kDa subunit; Oligosaccharyl transferase 48 kDa subunit

Immunogen: Recombinant full length protein of human OST48

Conjugate: Unconjugated

Modification: Unmodified