Osteocalcin Polyclonal Antibody-BS60987

Osteocalcin Polyclonal Antibody

Catalogue Numbers: BS60987-50, BS60987-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P02818

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Osteocalcin polyclonal antibody detects endogenous levels of Osteocalcin protein.

Extra Notes: Western blot analysis of Osteocalcin expression in HCT116 (A), HEK293T (B), PC12 (C), NIH3T3 (D) whole cell lysates.

Bioworld Molecular Weight: ~ 12 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: BGLAP; BGP; OC ; OCN; osteocalcin

Immunogen: Synthetic peptide, corresponding to Human Osteocalcin.

Conjugate: Unconjugated

Modification: Unmodified