Osteoprotegerin Rabbit Monoclonal Antibody-BS41371

Osteoprotegerin Rabbit Monoclonal Antibody

Catalogue Numbers:BS41371-50, BS41371-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: O00300

Host: Rabbit

Reactivity: Human

Applications: IHC, ICC/IF

All Applications: IHC 1:50~1:200 ICC/IF 1:50~1:200

Background: Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Osteoprotegerin Antibody detects endogenous levels of total Osteoprotegerin

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNFRSF11B; TR1;

Immunogen: A synthesized peptide derived from human Osteoprotegerin

Conjugate: Unconjugated

Modification: Unmodified