OTX2 Monoclonal Antibody - BT-MCA0962

OTX2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0962-50, BT-MCA0962-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

Research Areas: Epigenetics and nuclear signaling; Developmental biology; Stem cells; Neuroscience

Target Protein: OTX2

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Homeobox protein OTX2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P32243; Mouse: P80206

Synonyms: OTX2; Homeobox protein OTX2; Orthodenticle homolog 2

GeneID: Human: 5015

Research Use Only