Product Description

OTX2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11773-50, RA11773-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: orthodenticle homeobox 2 (OTX2) Homo sapiens This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012],

Reactivity: Human

Host: Mouse

Applications: WB, IHC-p, IF/ICC, FCM, ELISA

Alternate Names: OTX2, Homeobox protein OTX2, Orthodenticle homolog 2

Clonality: Monoclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Human Gene ID: 5015

Research Use Only