OTX2 Monoclonal Antibody - RA11773

OTX2 Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11773-50, RA11773-100

Citations, Manuals and MSDS Available upon request.

Background: orthodenticle homeobox 2 (OTX2) Homo sapiens This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6) . This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012],

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF/ICC; FCM; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 5015

SWISS: P32243

Source: Mouse

Research Use Only