p120 (phospho Tyr228) rabbit pAb - ES1522

p120 (phospho Tyr228) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1522-50, ES1522-100

Citations, Manuals and MSDS Available upon request.

Background: catenin delta 1 (CTNND1) Homo sapiens This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010],

Alternate Name: CTNND1; KIAA0384; Catenin delta-1; Cadherin-associated Src substrate; CAS; p120 catenin; p120 (ctn); p120 (cas)

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human Catenin-delta1 around the phosphorylation site of Tyr228. AA range:201-250

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 108kD

Human Gene ID: 1500

Human SWISS Prot NO: O60716

Subcellular Location: Cell junction, adherens junction. Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). Detected at cell-cell contacts (PubMed:15240885, PubMed:17047063). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm (PubMed:17047063). CDH1 enhances cell membrane localization (PubMed:15240885). Isoforms 4A and 1AB are excluded from the nucleus (PubMed:11896187).; [Isoform 1A]: Nucleus.; [Isoform 2A]: Nucleus.; [Isoform 3A]: Nucleus.

Research Use Only