Product Description

p21 (Acetyl Lys154) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28315-50, RA28315-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression., induction:By p53, mezerein (antileukemic compound) and interferon beta., PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA., similarity:Belongs to the CDI family., tissue specificity:Expressed in all adult human tissues, with 5-fold lower levels observed in the brain.,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1;Melanoma differentiation-associated protein 6;MDA-6;p21)

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 130

Protein Molecular Weight (kDa): 130

Storage: -20°C/1 year

Human Gene ID: 1026

Human SwissProt Number: P38936

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only