p21 Monoclonal Antibody-MB11349

p21 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11349-50, MB11349-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P38936

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1/500-1/1000

Background: The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of p21 in MCF-7Lysates using p21 antibody.

Bioworld Molecular Weight: Calculated MW: 18 kDa; Observed MW: 21 kDa

Specificity: IgG

Alternative Name: CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21

Immunogen: A synthetic peptide of human p21

Conjugate: Unconjugated

Modification: Unmodified