Reed Biotech
P27 Kip1 Mouse Monoclonal Antibody (1A7) - RA11779
P27 Kip1 Mouse Monoclonal Antibody (1A7) - RA11779
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P27 Kip1 Mouse Monoclonal Antibody (1A7)
Sizes: 50μL, 100μL
Catalogue Numbers: RA11779-50, RA11779-100
Lead times: 1-2 weeks, if manufacturer has product in stock
Manufacturer/Ship Location: China
Background: Cyclin dependent kinase inhibitor 1B (CDKN1B) Homo sapiens This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.
Reactivity: Human, Mouse, Rat
Host: Mouse
Applications: IHC-p, WB
Clonality: Monoclonal
Dilution: IHC-p1:50-200, WB 1:1000-2000
Storage: -20°C/1 year
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.35% sodium azide.
Protein Molecular Weight(KDa): 27
Molecular Weight: 27
Research Use Only
