Product Description

P2RY2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7856-50, BS7856-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Nucleotides are emerging as important extracellμlar signaling molecμles that mediate several effects, such as proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellμlar ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellμlar nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellμlar nucleotides. The P2Y receptors are differentially expressed in several tissue types, such as heart, lung and brain. However, all P2Y receptors are expressed in leukocytes, which suggests a role for the P2Y receptor family in the activation of leukocytes and platelets in response to inflammation or vascμlar damage.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF

Alternate Names: ATP receptor, HP2U, Human P2U nucleotide receptor mRNA complete cds, MGC20088, MGC40010, P2RU1, P2RY2, P2RY2_HUMAN, P2U, P2U nucleotide receptor, P2U purinoceptor 1, P2U receptor 1, P2U1, P2UR, P2Y purinoceptor 2, P2Y2, P2Y2R, Purinergic receptor, Purinergic receptor P2Y G protein coupled 2, Purinergic receptor P2Y2, Purinoceptor P2Y2,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human P2RY2.

Dilution: WB: 1:500~1:2000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: P2RY2 polyclonal antibody detects endogenous levels of P2RY2 protein.

Molecular Weight: ~ 50 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P41231

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only