Product Description

P2X3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28329-50, RA28329-100

Citations, Manuals and MSDS Available upon request.

Background: purinergic receptor P2X 3 (P2RX3) Homo sapiens The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5024

Protein MW (KDa): 44

SWISS: P56373

Source: Rabbit

Research Use Only