Product Description

p300 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16469-50, BZ16469-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellμlar p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regμlates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regμlation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimμlation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: ICC/IF, WB, IHC-F, IHC-P, ELISA

Alternate Names: EP300, P300, Histone acetyltransferase p300, p300 HAT, E1A-associated protein p300

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Synthesized peptide derived from the Internal region of human p300.

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 264 kDa, Observed MW: 300 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q09472

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only