P44/42 MAPK (ERK1/2) Monoclonal Antibody (6B1) - BT-MCA0973

P44/42 MAPK (ERK1/2) Monoclonal Antibody (6B1)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0973-20, BT-MCA0973-50, BT-MCA0973-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Research Areas: Signal transduction; Stem cells; Neuroscience

Target Protein: MAPK3

Applications: WB, IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P27361; P28482

Synonyms: MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p

GeneID: Human: 5594(5595)

Research Use Only