Product Description

p47 phox (Phospho Ser345) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28349-50, RA28349-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: disease:Defects in NCF1 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 1 (CGD1) [MIM:233700]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections., function:NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production)., online information:NCF1 deficiency database, similarity:Contains 1 PX (phox homology) domain., similarity:Contains 2 SH3 domains., subunit:Interacts with NOXA1.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Neutrophil cytosol factor 1 (NCF-1;47 kDa autosomal chronic granulomatous disease protein;47 kDa neutrophil oxidase factor;NCF-47K;Neutrophil NADPH oxidase factor 1;Nox organizer 2;Nox-organizing protein 2;SH3 and PX domain-containing protein 1A;p47-phox)

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 69

Protein Molecular Weight (kDa): 69

Storage: -20°C/1 year

Human Gene ID: 653361

Human SwissProt Number: P14598

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only