P4HB Monoclonal Antibody - BT-MCA2429

P4HB Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2429-50, BT-MCA2429-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

Research Areas: Others

Target Protein: P4HB

Applications: WB, IHC, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3F12C11D2

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: P4HB

Immunogen: Purified recombinant fragment of human P4HB (AA:309-508) expressed in mammalian.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 57.1kDa

UniProt Accession: P07237

Synonyms: DSI,GIT, PDI,PHDB, PDIA1,PO4DB, PO4HB,PROHB,CLCRP1, ERBA2L,P4Hbeta

GeneID: 5034

Research Use Only