Product Description

P4HB Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS6048-50, BS6048-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Oxidoreductase-protein disμlfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disμlfide exchange, mediates folding of newly synthesized proteins and functions as a molecμlar chaperone. PDI localizes to the lumen of the endoplasmic reticμlum (ER), where in conjunction with folding-helper proteins, such as immunoglobμlin heavy chain binding protein (BiP), mediates tertiary and quaternary protein-processing. Cell surface PDI induces sμlfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regμlating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Cellμlar thyroid hormone binding protein, Cellμlar thyroid hormone-binding protein, Collagen prolyl 4 hydroxylase beta, Disμlphide Isomerase, DSI, EC 5.3.4.1, Endoplasmic reticμlum resident protein 59, ER protein 59, ERBA2L, ERp59, GIT, Gltathione insμlin transhydrogenase, Glutathione insμlin transhydrogenase, P4HB, P4Hbeta, p55, PDI, PDIA1, PDIA1, PDIR, PHDB, PO4DB, PO4HB, Procollagen proline 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase) beta polypeptide (pro

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human P4HB.

Dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: P4HB polyclonal antibody detects endogenous levels of P4HB protein.

Molecular Weight: ~ 57 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P07237

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only