p52 S6 kinase rabbit pAb - ES5514

p52 S6 kinase rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5514-50, ES5514-100

Citations, Manuals and MSDS Available upon request.

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein., caution:Instead of Lys-820, Arg-820 is found at the binding site., domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site., function:May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily., similarity:Contains 1 MIT domain., similarity:Contains 1 PX (phox homology) domain., similarity:Contains 2 protein kinase domains., subcellular location:Also found in some small dot-like or ring-shaped early endosome structures., subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate., tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.,

Alternate Name: RPS6KC1; RPK118; Ribosomal protein S6 kinase delta-1; S6K-delta-1; 52 kDa ribosomal protein S6 kinase; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; SPHK1-binding protein

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human RPS6KC1. AA range:231-280

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 117kD

Human Gene ID: 26750

Human SWISS Prot NO: Q96S38

Subcellular Location: Cytoplasm. Membrane. Early endosome.

Research Use Only