Product Description

p53R2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28417-50, RA28417-100

Citations, Manuals and MSDS Available upon request.

Background: ribonucleotide reductase regulatory TP53 inducible subunit M2B (RRM2B) Homo sapiens This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: RRM2B; P53R2; Ribonucleoside-diphosphate reductase subunit M2 B; TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 50484

Protein MW (KDa): 40

SWISS: Q7LG56

Source: Rabbit

Research Use Only