p56Dok-2 (Phospho-Tyr351) Rabbit Polyclonal Antibody - BT-AP11739

p56Dok-2 (Phospho-Tyr351) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11739-20, BT-AP11739-50, BT-AP11739-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl)| a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Research Areas: Cancer; Signal transduction

Target Protein: DOK2

Applications: WB

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: p56Dok-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O60496; Mouse: O70469

Synonyms: p56Dok-2;Tyr351; Docking protein 2; Downstream of tyrosine kinase 2; p56;dok-2

GeneID: Human: 9046; Mouse: 13449

Research Use Only