p57 Kip2 Monoclonal Antibody-MB12177

p57 Kip2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12177-50, MB12177-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P49918

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20

Background: p27 Kip1 is a member of the Cip/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2/cyclin E and other CDK/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 32 kDa; Observed MW: 57 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of p57 Kip2 in A549, U2OS lysates using p57 Kip2 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p57 Kip2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2

Immunogen: A synthetic peptide of human p57 Kip2

Conjugate: Unconjugated

Modification: Unmodified