p60 Katanin Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11359-50, MB11359-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: O75449
Host: Rabbit
Reactivity: Human
Applications: WB
All Applications: WB: 1/500-1/1000
Background: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of p60 katanin in K562, HelaLysates using p60 Katanin antibody.
Bioworld Molecular Weight: Calculated MW: 56 kDa; Observed MW: 56 kDa
Specificity: IgG
Alternative Name: p60 katanin; Katanin p60 subunit A1
Immunogen: A synthetic peptide of human p60 katanin
Conjugate: Unconjugated
Modification: Unmodified