p73 rabbit pAb - ES4073

p73 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4073-50, ES4073-100

Citations, Manuals and MSDS Available upon request.

Background: tumor protein p73 (TP73) Homo sapiens This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011],

Alternate Name: TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human p73 around the non-acetylation site of Lys321. AA range:281-330

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 70kD

Human Gene ID: 7161

Human SWISS Prot NO: O15350

Subcellular Location: Nucleus. Cytoplasm. Accumulates in the nucleus in response to DNA damage.

Research Use Only