p95/NBS1 (Phospho-Ser343) Rabbit Polyclonal Antibody - BT-AP04003

p95/NBS1 (Phospho-Ser343) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04003-20, BT-AP04003-50, BT-AP04003-100

Citations, Manuals and MSDS Available upon request.

Background: Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Research Areas: Cancer; Epigenetics and nuclear signaling

Target Protein: NBN

Applications: WB

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: p95

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O60934; Mouse: Q9R207; Rat: Q9JIL9

Synonyms: p95/NBS1;Ser343; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1

GeneID: Human: 4683; Mouse: 27354; Rat: 85482

Research Use Only