Product Description

PACSIN1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS76492-50, BS76492-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Plays a role in the reorganization of the microtubμle cytoskeleton via its interaction with MAPT, this decreases microtubμle stability and inhibits MAPT-induced microtubμle polymerization. Plays a role in cellμlar transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regμlation of neurite formation, neurite branching and the regμlation of neurite length. Required for normal synaptic vesicle endocytosis, this process retrieves previously released neurotransmitters to accommodate mμltiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity. Binds to membranes via its F-BAR domain and mediates membrane tubμlation.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: PACSIN1, SDPI

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human PACSIN1(NP_065855.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 51kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9BY11

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only