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PADI4 Polyclonal Antibody - E-AB-52164

PADI4 Polyclonal Antibody - E-AB-52164

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PADI4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-52164-60, E-AB-52164-120, E-AB-52164-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PADI4

Target Synonym: EC 3.5.3.15; HL 60 PAD; HL-60 PAD; PAD 4; PAD; PADI 4; PADI 5; PADI H protein; Padi4; PADI4; PADI5; PDI 4; PDI 5; PDI4; PDI5; Peptidyl arginine deiminase type IV; Peptidyl arginine deiminase type V; Peptidylarginine deiminase IV; Protein arginine deiminase; Protein arginine deiminase type 4; Protein arginine deiminase type IV; Protein-arginine deiminase type IV; Protein-arginine deiminase type-4

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9UM07

Background: This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human PADI4

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Calculated MW: 74 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only