Product Description

PAFR/PAF Receptor Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65779-50, BS65779-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: P25105

Host: Rabbit

Reactivity: Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit,

Applications: WB, IHC-P

All Applications: WB=1:500-2000，IHC-P=1:100-500

Background: The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PAFR/PAF Receptor Polyclonal Antibody detects endogenous levels of PAFR/PAF Receptor protein.

Bioworld Molecular Weight: 38kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti-PTAFR at 1:200 dilution;, Primary: Anti- RAFR/PAF at 1/300 dilution, Tissue/cell: rat heart tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;Antigen retrieval: citrate buffer ( 0.01M, pH 6.0), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-PTAFR Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C,

Alternative Name: Platelet-activating factor receptor; PAF receptor; Ptafr; OTTHUMP00000004041; OTTMUSP00000010350; PAF R; PAF-R; PAFR; Platelet activating factor receptor; Platelet-activating factor receptor; PTAFR; PTAFR_HUMAN; RP23-470B20.1.聽聽

Immunogen: KLH conjugated synthetic peptide derived from human PAFR:231-342/342

Conjugate: Unconjugated

Modification: Unmodified