Product Description

PAIP1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11367-50, MB11367-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9H074

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IHC-F,IHC-P,ICC/IF,IP

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PAIP1 in Hela, 293T, mouse brainLysates using PAIP1 antibody.

Bioworld Molecular Weight: Calculated MW: 54 kDa; Observed MW: 54 kDa

Specificity: IgG

Alternative Name: poly(A) binding protein interacting protein 1

Immunogen: A synthetic peptide of human PAIP1

Conjugate: Unconjugated

Modification: Unmodified