PAK1 Monoclonal Antibody-MB11813

PAK1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11813-50, MB11813-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q13153

Host: Rabbit

Reactivity: Human, Mouse, Rat, Hamster

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 61 kDa; Observed MW: 61 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of PAK1 in 3T3 using PAK1 antibody, and DAPI., Western blot analysis of PAK1 in 3T3 lysates using PAK1 antibody., Western blot analysis of PAK1 in Hela, CHO-K1, C6, Jurkat lysates using PAK1 antibody, Immunohistochemistry analysis of paraffin-embedded Human colon cancer using PAK1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK

Immunogen: A synthetic peptide of human PAK1

Conjugate: Unconjugated

Modification: Unmodified