Product Description

PAK2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11370-50, MB11370-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q13177

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 58 kDa; Observed MW: 58 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PAK2 in K562, rat Brain, C6, 3T3, Hela lysates using PAK2 antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using PAK2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: PAK2; Serine/threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58

Immunogen: A synthetic peptide of human PAK2

Conjugate: Unconjugated

Modification: Unmodified