PAK6 rabbit pAb - ES8980

PAK6 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8980-50, ES8980-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 100-180

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 74kD

Human Gene ID: 56924

Human SWISS Prot NO: Q9NQU5

Subcellular Location: Cytoplasm. Nucleus. Cotranslocates into nucleus with AR in response to androgen induction.

Research Use Only