pan 14-3-3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A23674-20, A23674-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat, African green monkey
Protein Weight: 27kDa/28kDa
Observed Molecular Weight: 27-29kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 10971/7529/7532/7531/7534/7533/2810
SWISS: P27348/P31946/P61981/P62258/P63104/Q04917/P31947
Alternate Names: YWHA; S1C5; HS1; 14-3-3; pan 14-3-3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: pan 14-3-3
Research Use Only