Pan Lactic acid-Lysine Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18831-20, A18831-100
Citations, Manuals and MSDS Available upon request.
Background: Histone lysine lactation (Kla) is a newly discovered histone modification that regulates gene expression in macrophages. In M1 macrophages, lactic acid is derived from incompletely oxidized glucose and then produces lactyl-CoA, which is transferred via acetyltransferase p300 to the lysine tail of the histone. This modification is abundant in gene promoter regions that lack acetylation and are associated with gene expression activation.
Category: Other Modified Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat, Other (Wide Range)
Immunogen: Synthetic peptide
Species: Human
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: pan-Kla
Research Use Only