PAR2 Polyclonal Antibody - BT-AP12782

PAR2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12782-20, BT-AP12782-50, BT-AP12782-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.

Research Areas: Signal transduction

Target Protein: F2RL1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Proteinase-activated receptor 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P55085; Mouse: P55086; Rat: Q63645

Synonyms: Proteinase-activated receptor 2;PAR-2;Coagulation factor II receptor-like 1;G-protein coupled receptor 11;Thrombin receptor-like 1 [Cleaved into: Proteinase-activated receptor 2, alternate cle

GeneID: Human: 2150

Research Use Only