Product Description

PARD3 (F1161) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2104-50, BS2104-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Cellμlar asymmetry is critical for the development of mμlticellμlar organisms. PARD (partitioning-defective) proteins play important roles in asymmetric cell division and polarized growth. PARD3A (partitioning-defective 3), also known as Baz, ASIP (atypical PKC isotype-specific-interacting protein), PAR3, PARD3, PAR3α, Bazooka, SE2-5T2, SE2-5L16 or SE2-5LT1, is a 1, 356 amino acid protein that contains three PDZ domains and belongs to the PAR3 family of proteins. Expressed in a wide variety of tissues, PARD3A colocalizes with PARD6A/B and PKC ι at epithelial tight junctions and is believed to function as an adapter protein with an important role in the formation of normal tight junctions at epithelial cell-cell contacts. Due to alternative splicing events, PARD3A exists in at least ten isoforms, namely isoform A, isoform B, isoform C, isoform D, isoform E, isoform F, isoform Lb, isoform Sa, isoform Sb and isoform 10.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Partitioning defective 3 homolog, PAR-3, PARD-3, Atypical PKC isotype-specific-interacting protein, ASIP, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3, PAR3A

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 1131-1191 of Human PARD3.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PARD3 (F1161) polyclonal antibody detects endogenous levels of PARD3 protein.

Molecular Weight: ~ 181 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8TEW0

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only