PARD6A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-90474-60, E-AB-90474-120, E-AB-90474-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PARD6A
Target Synonym: PARD6A; PAR-6A; PAR6; PAR6C; PAR6alpha; TAX40; TIP-40
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9NPB6
Background: This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human PARD6A
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 37kDa
Observed MW: 37kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only