Product Description

PARD6A Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-90474-60, E-AB-90474-120, E-AB-90474-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PARD6A

Target Synonym: PARD6A; PAR-6A; PAR6; PAR6C; PAR6alpha; TAX40; TIP-40

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NPB6

Background: This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PARD6A

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 37kDa

Observed MW: 37kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only