PARG rabbit pAb - ES14260

PARG rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14260-50, ES14260-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the serine protease family of hydrolytic enzymes which contain a serine in their active site. The encoded protein may play a role in activation of the antiviral prodrug valacyclovir. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human PARG AA range: 140-190

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 8505

Human SWISS Prot NO: Q86W56

Subcellular Location: [Isoform 1]: Nucleus. Colocalizes with PCNA at replication foci (PubMed:21398629). Relocalizes to the cytoplasm in response to DNA damage (PubMed:16460818).; [Isoform 2]: Cytoplasm. Translocates to the nucleus in response to DNA damage.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm. Mitochondrion.; [Isoform 5]: Mitochondrion matrix.

Research Use Only