PARL Monoclonal Antibody - BT-MCA4436

PARL Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4436-50, BT-MCA4436-100

Citations, Manuals and MSDS Available upon request.

Background: PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Metabolism, Neuroscience, Cell biology, Cancer

Target Protein: PARL

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8C4B2

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: PARL

Immunogen: Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q9H300

Synonyms: PSARL, PSARL1, RHBDS1

GeneID: 55486

Research Use Only