PARL Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Number: RA11802-50, RA11802-100
Citations, Manuals and MSDS Available upon request.
Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: PARL; PSARL; Presenilins-associated rhomboid-like protein; mitochondrial; Mitochondrial intramembrane cleaving protease PARL
Background: presenilin associated rhomboid like(PARL) Homo sapiens This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016],
Applications: WB; ELISA
Species Cross-Reactivity: Human
GeneID (Human): 55486
SWISS: Q9H300
Source: Mouse
Research Use Only