PARL Monoclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA11802-50, RA11802-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: presenilin associated rhomboid like (PARL) Homo sapiens This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016], Reactivity: Human Host: Mouse Applications: WB, ELISA Alternate Names: PARL, PSARL, Presenilins-associated rhomboid-like protein, mitochondrial, Mitochondrial intramembrane cleaving protease PARL Clonality: Monoclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Storage: -20°C/1 year Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol. Human Gene ID: 55486 Research Use Only