PARP-1 (Acetyl-K521) rabbit pAb - ES8828

PARP-1 (Acetyl-K521) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8828-50, ES8828-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

Alternate Name: Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD (+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)

Source: Rabbit

Applications: WB; ELISA

Dilution: wb dilution 1:1000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized Acetyl peptide derived from human PARP-1. at AA range: K521

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 142

Human SWISS Prot NO: P09874

Subcellular Location: Nucleus. Nucleus, nucleolus. Chromosome. Localizes to sites of DNA damage.

Research Use Only