PARP Monoclonal Antibody (M3)
Sizes: 50μL, 100μL
Catalogue Number: RA11803-50, RA11803-100
Citations, Manuals and MSDS Available upon request.
Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Store At/In: -20°C/1 year
Recommended Dilutions: WB: 1:1000-3000
Alternative Names: Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)
Background: poly(ADP-ribose) polymerase 1(PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],
Applications: WB
Species Cross-Reactivity: Human; Chicken(testedbyourcustomer)
Molecular Weight: 116
GeneID (Human): 142
Protein MW (KDa): 116
SWISS: P09874
Source: Mouse
Research Use Only