PARP1 (10C2) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB3206-50, MB3206-100
Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Swiss-Prot: P09874
Host: Mouse
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG1
Bioworld Molecular Weight: Calculated MW: 113 kDa; Observed MW: 116 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of PARP1 in Hela, MCF-7 and Jurkat lysates using PARP antibody., Immunohistochemistry analysis of paraffin-embedded Human Tonsil Tissue using Cleaved PARP antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Western blot analysis of PARP1 in K562, Ramos, Jurkat lysates using PARP antibody., Western blot analysis of PARP1 in 3T3, Hela lysates using PARP1 antibody
Alternative Name: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Immunogen: Synthetic Peptide of Cleaved PARP
Conjugate: Unconjugated
Modification: Unmodified