PARP1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11372-50, MB11372-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P09874
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-F, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 113 kDa; Observed MW: 116,89 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of PARP1 in K562, 3T3, Hela lysates using PARP1 antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using PARP1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of PARP1 in Hela using PARP1 antibody, and DAPI
Alternative Name: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Immunogen: A synthetic peptide of human PARP1
Conjugate: Unconjugated
Modification: Unmodified