PARP11 Polyclonal Antibody - E-AB-11474

PARP11 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-11474-60, E-AB-11474-120, E-AB-11474-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PARP11

Target Synonym: 5330431N24Rik; AI851877; C12orf6; DKFZp779H0122; HIN1L; MIB006; OTTMUSP00000027219; Poly (ADP ribose) polymerase family member 11; RGD1561791

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NR21

Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.

Concentration: 0.4 mg/mL

Immunogen: Recombinant protein of human PARP11

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only