Pax-1 Polyclonal Antibody - BT-AP06945

Pax-1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06945-20, BT-AP06945-50, BT-AP06945-100

Citations, Manuals and MSDS Available upon request.

Background: PAX1 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: PAX1

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Pax-1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 46295

UniProt Accession: Human: P15863; Mouse: P09084

Synonyms: PAX1; HUP48; Paired box protein Pax-1; HuP48

GeneID: Human: 5075

Research Use Only