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PAX2 Polyclonal Antibody - E-AB-60827

PAX2 Polyclonal Antibody - E-AB-60827

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PAX2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60827-60, E-AB-60827-120, E-AB-60827-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PAX2

Target Synonym: PAX2; FSGS7; PAPRS

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q02962

Background: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human PAX2

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IF 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only