Product Description

PCDH15 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS70775-50, BS70775-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: PCDH15 (protocadherin 15), also known as USH1F or DFNB23, is a 1, 955 amino acid single-pass type I membrane protein that contains 11 cadherin domains and exists as mμltiple alternatively spliced isoforms. Expressed in testis, brain, lung, kidney and spleen, PCDH15 functions as a calcium-dependent cell-adhesion protein that is crucial for the maintenance of normal cochlear and retinal function. Defects in the gene encoding PCDH15 are associated with Usher syndrome type 1F (USH1F), Usher syndrome type 1D/F (USH1DF) and non-syndromic sensorineural deafness autosomal recessive type 23 (DFNB23), all of which are associated with deafness. Mμltiple isoforms of PCDH15 exist due to alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: USH1F, Protocadherin-15, Protocadherin 15

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human PCDH15.

Dilution: WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PCDH15 polyclonal antibody detects endogenous levels of PCDH15 protein.

Molecular Weight: ~ 100 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96QU1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only